Objective:
To predict the genes in the given nucleotide sequence (NM_000230.2) of human using the GenScan tool.
Theory:
• GenScan allows prediction of complete gene structures in genomic sequences, including exons, introns, promoters and poly-adenylation signals.
• GenScan differs from the majority of gene finding algorithms as it can identify complete, partial and multiple genes on both DNA strands. The program is based on a probabilistic model of gene structure/compositional properties and does not ....etc

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presented by:
Raphael Anstey
Matthieu Chardon
Travis Harper


What is a DNA Chip?
• Micro-Array containing all the genes (roughly 40,000) in the entire Human Genome (complete Genetic Code).
• Each known gene or “probe” occupies a particular “spot” on the chip, and varying levels of fluorescent activity show varying levels of gene activity in introduced genetic material.
• By introducing these samples or “targets” we can determine which genes are most active for traits, immunities, or any ....etc

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Outline
Introduction

Methods

Results

Conclusion

INTRODUCTION
Chronic diseases are caused by the interactions of various genes.
These are subject to interactions and environmental factors

Mutations

These entities and their interactions can be
represented well using graph networks
Contd..
Genomics and Phenomics

Integrated genomics–phenomics knowledge

Approach:
Generate Semantic Web based network data structures
Perform centrality analyses to rank genes
Contd..
Traditional methodolo ....etc

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1. ABSTRACT

microRNAs are small, regulatory ssRNA molecules involved in post-transcriptional gene silencing. Numerous miRNAs have been implicated in different types of cancers. The aim of this study is to create a bipartite graph connecting miRNAs and different cancers. We intend to identify miRNA hubs that are implicated in a large number of cancer types. Studying the function of such hub miRNAs is likely to shed light on the common pathogenesis mechanisms shared across the various cancer types .A combination of li ....etc

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ABSTRACT
With the dawn of the genome era computational methods in the automatic analysis of biological data have become increasingly important. The explosion in the production rate of expression level data has highlighted the need for automated techniques that help scientists analyze, understand, and cluster (sequence) the enormous amount of data that is being produced. Example of such problems are analyzing gene expression level data produced by microarray technology on the genomic scale, sequencing genes on the genomic sc ....etc

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The Human Genome Project
Vimal Jayaprakash & Sandhya.K
S1S2 Biotechnology and Biochemical Engineering
Mohandas College of Engineering & Technology
Nedumangad



Abstract
The Human Genome Project (HGP) is an international scientific research project with a primary goal of
determining the sequence of chemical base pairs which make up DNA and to identify and map the approximately
20,000–25,000 genes of the human genome from both a physical and functional sta ....etc

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Outline
Introduction

Methods

Results

Conclusion

INTRODUCTION
Chronic diseases are caused by the interactions of various genes.
These are subject to interactions and environmental factors

Mutations

These entities and their interactions can be
represented well using graph networks
Contd..
Genomics and Phenomics

Integrated genomics–phenomics knowledge

Approach:
Generate Semantic Web based network data structures
Perform centrality analyses to rank genes
Contd..
Traditional methodolo ....etc

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Abstract:
Imagine a device no bigger than a credit card that could extract your DNA from a drop of blood and map your entire genetic code while you wait. Within a short period of time the proneness to any illness or disease could be mapped and studied. This is not a snippet from a fiction movie. Biologists and engineers will have ONE working in just a few years, because the tool that makes it possible, a genetic microarray known as the DNA chip, already exists. Able to scrutinize tens of thousands of genes at once, the DNA chip's astonishin ....etc

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ABSTRACT

Rapid advances in bioinformatics are providing new hopes to patients of life threatening diseases. Gene chips will be able to screen heart attack and diabetics years before patients develop symptoms. In near future, patients will go to a doctorâ„¢s clinic with lab- on- a- chip devices. The device will inform the doctor in real time if the patientâ„¢s ailment will respond to a drug based on his DNA. These will help doctors diagnose life- ....etc

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Designer Babies
Athira S. and Sanjana A Nair
(S6, Biotechnology and Biochemical Engineering,
Mohandas College of Engineering and Technology,
Anad,Nedumangad-695544)



ABSTRACT
Every parent wants the best in the world for their child....but how would it be if parents could choose the sex of
their child? How would it be if intelligence, beauty, even the body type, colour of hair and eyes etc. was just a
matter of choice? With the advance in genetic engineeri ....etc

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Genetic programming has recently emerged as an important paradigm for automatic generation of computer programs. GP combines metaphors drawn from biological evolution with computer science techniques in order to produce algorithms and programs automatically.From the very beginning, man has tried to develop machines that can replace the need for human beings for many applications; machines that require very little support of human beings. Research is going on to develop machines that can produce high artificial components in the results, with le ....etc

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ABSTRACT
Bioinformatics is discipline which combines computer science, Biology, Information Technology. Bioinformatics used for storing, analysing, collecting large amount of biological information. Biological data include any type data related to plant, animal, yeast, fungi etc.
In this paper we represent how to determine genes in inherited diseases and to determine gene code for beneficial traits. Tools are used to find information about the function and location of particular genes. It gives the information of di ....etc

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Content
What is bioinformatics.
What is computational Biology.
Data mining.
Application of data mining.
Net accessible resources.
Sequence Analysis.
What can be Done with sequence Analysis.?
Identification of protein primary sequence from DNA sequence.
Tips for searching Database.
The process of Evolution.
Principle and their Importance.
Conclusion.

What is Bioinformatics.
Bioinformatics describe any use of computer to handle biological information. In practice, the definition used by most pe ....etc

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