The ability of molecules to serve as computer switches has been a major area of scientific research since the middle of the last century. Molecular switches, if these become a reality, will offer appreciable reduction in hardware size, since these are themselves very small. One can then imagine of bimolecular computer about 1/20th the size of present-day semiconductor-based computers. Small size and fast operation will account for the development of most modern computers. ....etc

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Visualization of Microarray Data
Contents:
Introduction
Visualization Methods
Visualization Tools
Comparison between Tools
Experiments
Conclusion
Introduction
Microarray
Advancing with numerous applications in gene expression, genotyping, cell biology.
Helps researchers to
Learn more about diseases.
Study of Cancer.
Overview
Visualization of Microarray Data
Heat Maps
Dendrograms
TreeMaps
Scatter-Plots (2-D/3-D).
Box Plot
Clusterview and Treeview.
organize and analyze the data in ma ....etc

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Expression and Regulation of Protein Complexes in Yeast

Structural Biology and Centre for Computational Biology, Hospital for Sick Children, 555 University Avenue, Toronto, M5G 1X8, Canada 2 Service de Conformation de Macromolecules Biologiques, Centre de Biologie Structurale et Bioinformatique, Université Libre de Bruxelles, CP263, Blvd. du Triomphe, 1050, Bruxelles, Belgium Multiprotein complexes play an essential role in many cellular processes.

But our knowledge of the mecha ....etc

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While magnetic and semi-conductor based information storage devices have been in use since the middle 1950 s, today s computers and volumes of information require increasingly more efficient and faster methods of storing data. While the speed of integrated circuit random access memory (RAM) has increased steadily over the past ten to fifteen years, the limits of these systems are rapidly approaching. In response to the rapidly changing face of computing and demand for

· physically smaller,

· greater capacity,

 ....etc

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Definition
Since the dawn of time, man has tried to record important events and techniques for everyday life. At first, it was sufficient to paint on the family cave wall how one hunted. Then came the people who invented spoken languages and the need arose to record what one was saying without hearing it firsthand. Therefore, years later, earlier scholars invented writing to convey what was being said. Pictures gave way to letters which represented spoken sounds. Eventually clay tablets gave way to parchment, which gave way to paper. Paper was ....etc

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Mining Microarray



ORIGIN OF MICROARRAY


-Many experiments on molecular biology since 1970

-Development of DNA sequencing

-Polymerase Chain Reaction (PCR)

WHAT IS MICROARRAY ?


-Ordered set of DNA molecule of known sequence

-May consists of few hundreds to hundred of thousands

-Individual feature in the array at precisely definite location of the substrate

-Identity of the DNA molecule never changes


IMPORTANCE OF MICROARRAY ....etc

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Protein-based optical memory storage

While magnetic and semi-conductor based information storage devices have been in use since the middle 1950 s, today s computers and volumes of information require increasingly more efficient and faster methods of storing data. While the speed of integrated circuit random access memory (RAM) has increased steadily over the past ten to fifteen years, the limits of these systems are rapidly approaching. In response to the rapidly changing face of computing and dema ....etc

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Protein chips also referred to as protein arrays or protein microarrays, are modeled after DNA microarrays. The success of DNA microarrays in large-scale genomic experiments inspired researchers to develop similar technology to enable large-scale, high-throughput proteomic experiments. Protein chips enable researchers to quickly and easily survey the entire proteome of a cell within an organism. They also allow researchers to automate and parallelize protein experiments.Protein chips were first developed in 2000 by researchers at Harvard Univer ....etc

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Automatic Gridding for DNA Microarray Image Using Image Projection Profile



Abstract

DNA microarray is powerful tool and widely used in many areas.
DNA microarray is produced from control and test tissue sample cDNAs, which
are labeled with two different fluorescent dyes. After hybridization using a laser
scanner, microarray images are obtained. Image analysis play an important role
in extracting fluorescence intensity from microarray image. First step ....etc

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Abstract—Microarray technology is one of the important biotechnological means that allows to record the expression levels of thousands of genes simultaneously within a number of different samples. An important application of microarray gene expression data in functional genomics is to classify samples according to their gene expression profiles. Among the large amount of genes presented in gene expression data, only a small fraction of them is effective for performing a certain diagnostic test. Hence, one of the major tasks with the gene expr ....etc

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