Introduction
Monoclonal antibodies are antibodies which
have a single, selected specificity and which
are continuously secreted by “immortalised”
hybridoma cells. A hybridoma is a biologically
constructed hybrid of a mortal, antibody-
producing, lymphoid cell, and a
malignant, or “immortal”, myeloma cell. Following
the discovery of hybridoma technology
in 1975 (2), developments in mAb
production and in their application have had
profound implications not only on medical
research, diagnosis and therapy, but also on
biolog ....etc

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Antibody Purification



Introduction
The diversity of the antibody-antigen interaction and our ability to manipulate the characteristics
of the interaction has created many uses for antibodies and antibody fragments,
both for immunochemical techniques within general research and for therapeutic and
diagnostic applications.
The use of recombinant technology opens up the potential to create an infinite number of
combinations between immunoglobulins, immuno ....etc

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