19-02-2011, 04:27 PM
presented by:
Harshil Sanghani
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Medical applications of NANOTECHNOLOGY
Nanotechnology for bone disease
• Bone related infectious disease like osteomyelitis & prosthesis are of great concern to the modern world.
• These involve the biofilms and are often chronic and painful
• Biofilms are infections whereby bacteria form a robust colony protected by a sticky slime matrix from the body's immune system and are resistant to antibiotic treatment.
• Magnetic nanoparticles can be directed in the presence of a magnetic field to any part of the body, allowing for site-specific drug delivery. Magnetic nanoparticles have also shown promise to enhance bone cell functions and possibly provide an immediate increase in bone density.
Artificial mitochondria
• Tissues suffering from ischemic (tissue injury caused by loss of blood flow) injury might not be able to properly metabolize oxygen.
• Particularly mitochondria will fail in doing so.
• Increased oxygen levels in the presence of nonfunctional or partially functional mitochondria will be ineffective in restoring the tissue.
• . The direct release of ATP, coupled with selective release or absorption of critical metabolites should be effective in restoring cellular function even when mitochondrial function had been compromised. For this nano-materials are used.
Providing oxygen
A simple method of improving the levels of available oxygen despite reduced blood flow would be to provide an "artificial red blood cell.“
Diameter of the RBCs would be about 100 nanometers
In treatment of CANCER
• By the use of Raman spectroscopy it is possible not only to monitor and detect nanomaterials but also to detect the cancer cells with the help of carbon nanotubes.
• Carbon nanotubes can be inserted into the blood stream or the lymphatic system. It can detect the presence of cancerous tumours.
• It gets associated to the cancerous cells.
• With the help of Raman spectroscopy heat is provided to these nanotubes which kills the cancerous tumour.