matlab code for brain abnormality detection in mr images
#1
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hi I am sai vivek and I would like get the matlab code for the detection of abnormality in the images of brain. I need code urgently. hope you would help me with this issue
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#2
Nowadays, automatic defects detection in MR images is very
important in many diagnostic and therapeutic applications.
Because of high quantity data in MR images and blurred
boundaries, tumor segmentation and classification is very hard.
This paper has introduced one automatic brain tumor detection
method to increase the accuracy and yield and decrease the
diagnosis time. The goal is classifying the tissues to two classes of
normal and abnormal. MR images that have been used here are
MR images from normal and abnormal brain tissues. Here, it is
tried to give clear description from brain tissues using Zernike
Moments , Geometric Moment Invariants, energy, entropy,
contrast and some other statistic features such as mean, median,
variance, correlation, values of maximum and minimum intensity .
It is used from a feature selection method to reduce the feature
space too. this method uses from neural network to do this
classification. The purpose of this project is to classify the brain
tissues to normal and abnormal classes automatically, that saves
the radiologist time, increases accuracy and yield of diagnosis.

INTRODUCTION
Digital image process [2] found its application in medical
image analysis and engineers are coming up with different
techniques to help physician and surgeons in image analysis
needed for diagnosis .During diagnosis usually a specific part
of body is scanned and that image is then physically analyzed
by surgeons.
In today’s world’s maintaining large database of brain
Abnormality (MR) magnetic resonance images is a
complicated task as the data is not indexed and cannot be
searched on the basis of attributes like location or size.
1.1 MR Image
Magnetic resonance imaging technique uses radio wave
pulses and magnetic field to scan organs and structure inside
the body .MRI test gives various type of information required
by the doctors for the treatment purpose .This technique gives
every information about internal body structure that can be
obtained by any other type of scans like X-ray, ultrasound etc
This technique has the advantage that it provides more
information compared to the other available techniques.
For an MRI test, the part of the body for which the
information of its internal structure is required is placed inside
the machine that has strong electromagnets to produce
magnetic field. The output of MR scans is digital image in
DICOM format that can be saved and stored for analysis and
future reference. The MR image can be viewed and
transported to places such as clinics or operating room where
doctors may require it.
Scanning of brain is done to obtain the internal structure of
brain using computer technology. A MR scan consists of an
image of internal structure of brain. Magnetic resonance
imaging is a powerful tool for investigating brain for
Abnormality.
The advantage of detecting brain Abnormality by MR images
are: -
 There is no need to inject drug into the human body
 The entire process has not any radiation damage and
is completely safe.
 Patient’s body is not physically hampered for
diagnosis purpose.
Using MRI scans, physicians can diagnose or monitors
treatments of various types of diseases
 Abnormalities in the brain and spinal cord
 Tumors and other abnormalities in various parts of the
body
 Injuries or abnormalities of the joints
 Certain heart problems
 Diseases of the liver and other organs
 Suspected uterine abnormalities in women undergoing
evaluation for infertility
1.2 Risks/Benefits
MR scans produce high-energy radiation that can cause
damage to DNA.
 Dyes that are inserted can be harmful and can cause
damage to internal brain cells.
 Medication patches can cause a skin burn.
 The apparatus used to monitor an electrocardiogram
(ECG) trace or respiration during a scan must be placed
carefully to avoid causing a skin burn.
Sometimes MR images suffer from noises due to technical or
human error. These errors are:-
1.2.1 Salt and Pepper Noise
It is also known as impulse noise. This type of noise occurs
due to sharp and sudden disturbances in image signal at the
time of acquiring the image. It appears as random white and
black cells scattered all over the image.
1.2.2 Poisson Noise
Poisson noise is signal-dependent, that is often seen in photon
images[6]. The variance of the noise is proportional to the
original image values. The noise model is described as
D (m, n) ~1/λ[Poisson {o (m, n)}]
Where o*(m, n) and d*(m, n) mean the pixel values in the
original and degraded images, respectively. The degraded
image is generated by multiplying the original pixel values by
λ and by using these as the input to a random number
generator which Returns Poison distributed values.
1.2.3 Median Filter
Median filter is used to reduce noise in an image [2]. The best
known order statics filter is the median filter, which as its
name implies replace the value of a pixel by the median of the
intensity levels in the neighborhood of that pixel. In a median
filter the median intensity value of the pixels within the
window becomes the output intensity value of the pixel being
processed. Median filter preserves edges in an image while
reducing random noise.
While acquiring MR images from the computer aided
machines. Due to human error noise may occur which may
lead to problem in Abnormality detection so it is very
necessary to remove all the noise from MR images before
diagnosis.
2. LITERATURE SURVEY
Some works are available in literature on automatic brain
Abnormality detection technique. Some of the techniques
are discussed in this section.
K Somojundran et al proposed [1] pixel to pixel approach for
detecting brain Abnormality by finding the difference in
intensity of pixels. In his technique, Abnormality location is
detected by finding regional maxima. In these technique first
MR slices containing abnormality is separated from normal
MR slices, for this purpose vertical symmetry is checked.
Hence fuzzy segmentation is done to discriminate between
normal and abnormal slices .After segmentation, region of
abnormality in MR images has increased intensity which
possesses local maxima hence abnormal region is detected
using extended maxima transform. His technique suffers from
disadvantage and yields poor result as it is based on the
contrast of MR images which can change.
Rechna Rana et al. [7] used fuzzy c-mean algorithm for
detecting tumorous regain. This technique worked well only
for hyper intensity (fully enhanced) Abnormality, this is due
to fact that fuzzy models typically used thresholding
techniques or morphological operations(erosion or dilation) as
pre or post processing, leading to the border enhancing or
non- enhancing abnormalities having very few bright pixels.
This technique had disadvantage that it yields very poor
performance when detecting non-enhanced Abnormality.
In this paper it is pointed out that for detection of abnormality
in brain using K-means clustering algorithm ,it is necessary to
essentially define the number of cluster K .But as it not
possible to initially define the number of clusters in this case
it is inefficient.
P. Marcon et al.[8] proposed technique to detect brain
Abnormality using chan-vese algorithm. There are three steps
involved in it
 Data acquisition: - MR images is normally stored and
transmitted in (DICOM) format. This is standard for
handling, storing, printing and transmitting information
in medical image. It includes file format protocol and a
network communication (Application layer protocol).
 Image registration: -It is a technique to transform
different set of data into one coordinate system. MR
image may be affected by small patient movements
caused by heart beating or breathing during MRI test.
So it is necessary to perform image registration for MR
images. It can be done in two ways
 Detect interhemispheric fissure
 Intensity base segmentation method
 Segmentation based on chan-vese algorithm:-this
algorithm for segmentation create 3D binary matrix of
abnormality .the output of this algorithm is image
depicting abnormality with high contrast.
This technique detects the brain Abnormality very efficiently
and accurately. But, it has a disadvantage that, it needs image
registration and chan-vese algorithm has high time
complexity.
Rupinderal Singh et al. [9] proposed Abnormality detection
technique using an artificial neural network and used modified
canny edge detection technique to detect the edge of skull.
The motive to detect edge of skull in MR images is to
significantly reduce the amount of data in image. Canny edge
detection algorithm preserves the structural properties of
image that can be used for further preprocessing .an artificial
neural network works in the same way as biological nervous
system i.e. as brain processes information ANN can be
configured for abnormality detection through training. .This
technique successfully classified infected brain from the set of
healthy brain.
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