Please give the article about boron chemistry and application of cancer treatment
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Recently, boron compounds have attracted increasing attention both in academic labs and in the pharmaceutical industry. Boron, in particular isotope (10) B, has the unique ability to absorb a slow neutron to initiate a nuclear reaction with release of energetic particles such as a and Li particles, which is not observed in its carbon analogues. The concept of nuclear capture reaction has been adopted in radiotherapy and is used in boron neutron capture therapy (BNCT). BNCT is a potentially promising treatment for malignant brain tumors as well as other types of cancer, despite the limited scarcity of neutron sources. There is a need in advanced research centers to build high boron compounds as BNCT agents and to develop more efficient drug carriers. This review discusses recent work on the development of boron-based therapeutic nanomaterials as BNCT agents.