1. True about Chondrosarcoma are
a. It is a malignant tumor
b. It is a tumor that forms bone
c. 25% of all biopsy malignant bone tumors are chondrosarcomas
d. Synovial chondromatosis can become a chondrosarcoma
e. 8-17% of all biopsied primary bone tumors are chondrosarcomas
2. Which of the following can progress to become a chondrosarcoma
a. Enchondroma
b. Osteochondroma
c. Chondromixoid Fibroma
d. Chondroblastoma
e. Synovial chondromatosis
3. Myxoid chondrosarcoma belongs to what degree of chondrosarcoma
a. Grade 1
b. Grade 2
c. 3rd grade
d. Any
4. Find the true statement (s)
a. Chondrosarcoma is common in children
b. 50% of patients are over 40 years of age with an average peak incidence of 50 years
c. The ratio between men and women is 1.5: 1
d. The clinical presentation is usually insidious onset pain
e. Chondrosarcoma may also present with palpable mass (28%) or pathological fracture (27%)
5. Which of the following is the least commonly affected site for chondrosarcoma?
a. Pelvis
b. Proximal femur
c. Proximal humerus
d. Hands and feet
6. Find the false statement / s
a. A central chondroid tumor with pain or increased growth should be considered as chondrosarcoma until proven otherwise by biopsy or benign clinical progression
b. Chondrosarcoma is suggested if the level of scintigraphic activity in the lesion is greater than in the anterior iliac crest
c. Calcification occurs in 29% of chondrosarcomas on CT
d. Deep endosteal cortical scalloping (greater than 2 / 3rds) is suggestive of chondrosarcoma as opposed to chondroma
7. The radiographic features of Chondrosarcoma are all except
a. 75% of cases show calcification
b. The small chondrosarcoma of low grade can not be differentiated from a chondroma, which appears as a well defined lytic lesion with mineralization of the chondroid matrix.
c. Plain radiography may not accurately define spinal cord involvement
d. Periosteal reaction is a rare feature of chondrosarcomas
8. The MRI characteristics of chondrosarcoma are
a. The lesion is slightly hypointense for the T1 muscle and may show focal areas of hyperintensity due to trapped areas of bone marrow
b. Malignant cartilage shows a higher characteristic intensity of the signal in the T2 images and a multilobulated appearance
c. The mineralization of the matrix manifests as focal areas of signal vacuum
d. Most chondrosarcomas are very well vascularized and the improvement after IV contrast is excellent
e. T2 images have been shown to be valuable in the identification of dedifferentiation, in which case a region of intermediate signal intensity is seen adjacent to the typical mass of hyperintense chondral tumor
9. Which of the following are true with respect to a secondary peripheral chondrosarcoma that develops from an osteochondroma
a. Most osteochondromas have cartilage capsules no thicker than 5 mm and a capsule of more than 20 mm is likely to be malignant
b. The radiological characteristics of the malignant change consist in the destruction of part of the calcified cap or ossified stem of the osteochondroma
c. Clinically malignant change should be suspected if pain develops or continuous growth occurs after skeletal maturity
d. X-rays are generally used to measure the thickness of the cartilage capsule of the osteochondroma
10. True statement (s) on Chondrosarcoma periosteum (a rare form of chondrosarcoma)
a. Usually involves long bones
b. Commonly involves distal metaphysis of the humerus and proximal humerus
c. More common in men with a wide range of presentation
d. Radiologically, a calcified juxtacortical mass is observed, with cortical thickening and periosteal reaction
e. Involvement of the bone marrow is rare
F. The prognosis is poor.